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Tocris/PBIT/5930/50/50毫克

商品编号： 5930/50

品牌： Tocris Bioscience

市场价： ¥8900.00

美元价： 5340.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:JARID1(JumonjiAT-RichInteractiveDomain1)inhibitor

ChemicalName:2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

JARID1(JumonjiAT-RichInteractiveDomain1)inhibitor(IC₅₀valuesare3,4.9and6μMforJARID1B,1Aand1C,respectively).SelectiveforJARID1overUTXandJMJD3.IncreaseslevelsofmethylatedH3K4inJARIDB1-transfectedHeLacellsandMCF7cells.InhibitsproliferationofbreastcancercelllinesexpressinghighlevelsofJARIDB1.

TechnicalData

M.Wt	241.31
Formula	C₁₄H₁₁NOS
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	2514-30-9
PubChemID	935415
InChIKey	KRXMYBAZKJBJAB-UHFFFAOYSA-N
Smiles	CC1=CC=C(N2SC3=C(C2=O)C=CC=C3)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	24.13	100
	ethanol	4.83	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight241.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	4.14mL	20.72mL	41.44mL
5mM	0.83mL	4.14mL	8.29mL
10mM	0.41mL	2.07mL	4.14mL
50mM	0.08mL	0.41mL	0.83mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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