Tocris/PCI 34051/4643/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PCI 34051/4643/50/50毫克

Tocris/PCI 34051/4643/50/50毫克

商品编号： 4643/50

品牌： Tocris Bioscience

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveHDAC8inhibitor

ChemicalName:N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivehistonedeacetylase8(HDAC8)inhibitor(IC₅₀=10nM).Displays>200foldselectivityoverHDACisoforms1,2,3,6and10.InducesapoptosisincelllinesderivedfromTcelllymphomasorleukemias.

CompoundLibraries

PCI34051isalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	296.32
Formula	C₁₇H₁₆N₂O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	950762-95-5
PubChemID	24753719
InChIKey	AJRGHIGYPXNABY-UHFFFAOYSA-N
Smiles	O=C(NO)C1=CC=C2C(N(CC3=CC=C(OC)C=C3)C=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.NaOH	5.93	20
	DMSO	29.63	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight296.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.37mL	16.87mL	33.75mL
5mM	0.67mL	3.37mL	6.75mL
10mM	0.34mL	1.69mL	3.37mL
50mM	0.07mL	0.34mL	0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

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ProductDatasheets