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Tocris Bioscience(优势品牌)
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/PD 146176/2850/10/10 mg
商品详细Tocris/PD 146176/2850/10/10 mg
Tocris/PD 146176/2850/10/10 mg
Tocris/PD 146176/2850/10/10 mg
商品编号: 2850/10
品牌: Tocris Bioscience
市场价: ¥2580.00
美元价: 1548.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Selective15-lipoxygenaseinhibitor
ChemicalName:6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Specific,non-competitve15-lipoxygenase(15-LOX)inhibitor(Ki=197nM)thathasnodemonstrableeffecton5-LOX,12-LOX,COX-1orCOX-2(IC50=0.54μMfor15-LOXinrabbitreticulocytes).Lacksnon-specificantioxidantpropertiesandpreventsatherogenesisviaregulationofmonocyte-macrophageenrichmentinvivo.

TechnicalData

M.Wt237.32
FormulaC15H11NS
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber4079-26-9
PubChemID297589
InChIKeyZGOOPZVQMLHPFM-UHFFFAOYSA-N
SmilesC12=CC=CC=C1C3=C(C(C=CC=C4)=C4SC3)N2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23.73100
ethanol11.8750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight237.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.21mL21.07mL42.14mL
5mM0.84mL4.21mL8.43mL
10mM0.42mL2.11mL4.21mL
50mM0.08mL0.42mL0.84mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet