Tocris/PD 158780/2615/10/10 mg-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > kinase > Tocris/PD 158780/2615/10/10 mg

商品详细Tocris/PD 158780/2615/10/10 mg

Tocris/PD 158780/2615/10/10 mg

商品编号： 2615/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：激酶

公司分类： kinase

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:PotentErbBreceptorfamilyinhibitor

ChemicalName:N⁴-(3-Bromophenyl)-N⁶-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitorofErbBreceptorfamilytyrosinekinases(IC₅₀valuesare0.008,49and52nMforEGFR,ErbB2andErbB2/ErbB4respectively)thatdoesnotinhibitFGForPDGF-mediatedtyrosinephosphorylation.InducesG₁cellcyclearrestinMCF10AcellsandisantiproliferativeinA431humanepidermalcarcinomacells.

CompoundLibraries

PD158780isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	330.18
Formula	C₁₄H₁₂BrN₅
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	171179-06-9
PubChemID	4707
InChIKey	KFHMLBXBRCITHF-UHFFFAOYSA-N
Smiles	CNC1=NC=C2N=CN=C(NC3=CC=CC(Br)=C3)C2=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	33.01	100
	ethanol	8.25	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight330.18.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.03mL	15.14mL	30.29mL
5mM	0.61mL	3.03mL	6.06mL
10mM	0.3mL	1.51mL	3.03mL
50mM	0.06mL	0.3mL	0.61mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage:

BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets