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当前位置: 首页 > 产品中心 > kinase > Tocris/PD 161570/3724/50/50 mg
商品详细Tocris/PD 161570/3724/50/50 mg
Tocris/PD 161570/3724/50/50 mg
Tocris/PD 161570/3724/50/50 mg
商品编号: 3724/50
品牌: Tocris Bioscience
市场价: ¥19300.00
美元价: 11580.00
产地: 美国(厂家直采)
公司:
产品分类: 激酶
公司分类: kinase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:SelectiveFGFRinhibitor
ChemicalName:N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveFGFRinhibitor(IC50valuesare40,262and3700nMforFGFR,PDGFRandEGFRrespectively).InhibitsFGFRreceptorphosphorylation(IC50=622nM)andgrowthofA121cellsinvitro.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

CompoundLibraries

PD161570isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt532.51
FormulaC26H35Cl2N7O
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber192705-80-9
PubChemID5328135
InChIKeyMKVMEJKNLUWFSQ-UHFFFAOYSA-N
SmilesClC1=CC=CC(Cl)=C1C3=CC2=CN=C(NCCCCN(CC)CC)N=C2N=C3NC(NC(C)(C)C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO53.25100
ethanol53.25100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight532.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.88mL9.39mL18.78mL
5mM0.38mL1.88mL3.76mL
10mM0.19mL0.94mL1.88mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet