Tocris/PD 184352/4237/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PD 184352/4237/10/10 mg

Tocris/PD 184352/4237/10/10 mg

商品编号： 4237/10

品牌： Tocris Bioscience

市场价： ¥4700.00

美元价： 2820.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveMEKinhibitor

AlternativeNames:CI-1040

ChemicalName:2-[(2-Chloro-4-iodophenyl)amino]-N-cyclopropylmethoxy)-3,4-difluorobenzamide

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveMEKinhibitor(K_i=300nMinvitro).SuppressesFGF-mediatedangiogenesisinvivoanddecreasesVEGFexpression.Enhancesthetherapeuticefficacyoftaxol(Cat.No.1097)invivo.Orallyactive.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt	478.66
Formula	C₁₇H₁₄ClF₂IN₂O₂
Storage	Storeat+4°C
CASNumber	212631-79-3
PubChemID	6918454
InChIKey	GFMMXOIFOQCCGU-UHFFFAOYSA-N
Smiles	FC1=C(NC2=CC=C(I)C=C2Cl)C(C(NOCC3CC3)=O)=CC=C1F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	47.87	100
	ethanol	11.97	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight478.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.09mL	10.45mL	20.89mL
5mM	0.42mL	2.09mL	4.18mL
10mM	0.21mL	1.04mL	2.09mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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