Tocris/PF 04457845/6374/25/25 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PF 04457845/6374/25/25 mg

Tocris/PF 04457845/6374/25/25 mg

商品编号： 6374/25

品牌： Tocris Bioscience

市场价： ¥5900.00

美元价： 3540.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveirreversIBLeFAAHinhibitor

ChemicalName:N-3-Pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveirreversibleFAAHinhibitor(IC₅₀=7.2nM).SelectiveforFAAHoverapanelofotherserinehydrolases.Exhibitsefficacyinaratinflammatorypainmodel.Orallybioavailableandbrainpenetrant.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc

TechnicalData

M.Wt	455.43
Formula	C₂₃H₂₀F₃N₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1020315-31-4
PubChemID	24771824
InChIKey	BATCTBJIJJEPHM-UHFFFAOYSA-N
Smiles	FC(F)(C1=CC=C(N=C1)OC2=CC=CC(/C=C3CCN(C(NC4=CC=CN=N4)=O)CC3)=C2)F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	45.54	100
	ethanol	9.11	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight455.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.2mL	10.98mL	21.96mL
5mM	0.44mL	2.2mL	4.39mL
10mM	0.22mL	1.1mL	2.2mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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