Tocris/PF 05175157/5790/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PF 05175157/5790/10/10 mg

Tocris/PF 05175157/5790/10/10 mg

商品编号： 5790/10

品牌： Tocris Bioscience

市场价： ¥2980.00

美元价： 1788.00

产地：美国(厂家直采)

公司：

产品分类：脂质代谢研究

公司分类： Lipid_metabolism_study

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Acetyl-CoAcarboxylase(ACC)1and2inhibitor

ChemicalName:1,4-Dihydro-1'-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4'-piperidin]-7(6H)-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Acetyl-CoAcarboxylase(ACC)2and1inhibitor(IC₅₀valuesare45and98nM,respectively).Reduceshepaticandskeletalmusclemalonyl-CoAlevelsinrats.Alsoinhibitshepaticdenovolipogenesisandreduceswholebodyrespiratoryexchangeratioinrats.Orallybioavailable.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt	405.49
Formula	C₂₃H₂₇N₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1301214-47-0
PubChemID	52934180
InChIKey	BDXXSFOJPYSYOC-UHFFFAOYSA-N
Smiles	O=C(C4=CC=C(N=C(C)N5)C5=C4)N1CCC(CC(C=NN3C(C)C)=C3C(C2)=O)2CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	20.27	50
	ethanol	8.11	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight405.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.47mL	12.33mL	24.66mL
5mM	0.49mL	2.47mL	4.93mL
10mM	0.25mL	1.23mL	2.47mL
50mM	0.05mL	0.25mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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