Tocris/PF 05180999/6405/5/5 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PF 05180999/6405/5/5 mg

Tocris/PF 05180999/6405/5/5 mg

商品编号： 6405/5

品牌： Tocris Bioscience

市场价： ¥1580.00

美元价： 948.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectivePDE2Ainhibitor

ChemicalName:4-(1-Azetidinyl)-7-methyl-5-[1-methyl-5-[5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-4-yl]-imidazo[5,1-f][1,2,4]triazine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivePDE2Ainhibitor(IC₅₀=1nM).Exhibits2000-foldselectivityforPDE2AoverPDE10A.Brainpenetrant.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt	414.39
Formula	C₁₉H₁₇F₃N₈
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1394033-54-5
Smiles	CC1=NC(C2=C(C3=NC=C(C(F)(F)F)C=C3)N(C)N=C2)=C4N1N=CN=C4N5CCC5

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	20.72	50
	ethanol	20.72	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight414.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.41mL	12.07mL	24.13mL
5mM	0.48mL	2.41mL	4.83mL
10mM	0.24mL	1.21mL	2.41mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets