Tocris/PF 06281355/6004/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PF 06281355/6004/10/10 mg

Tocris/PF 06281355/6004/10/10 mg

商品编号： 6004/10

品牌： Tocris Bioscience

市场价： ¥3100.00

美元价： 1860.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Selectivemyeloperoxidase(MPO)inhibitor

ChemicalName:6-(2,5-Dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivemyeloperoxidase(MPO)inhibitor(IC₅₀=1.5μMinLPS-stimulatedhumanwholeblood).SelectiveforMPOoverapanelof50receptors,enzymes,ionchannelsandtransporters,includingthyroidperoxidase.InhibitsMPOactivityinperitoneallavageandplasmainamurineperitonitismodel.Alsoreduceslungedemainamurinepulmonaryimmunecomplexvasculitismodel.Orallybioavailable.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc

TechnicalData

M.Wt	321.35
Formula	C₁₄H₁₅N₃O₄S
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	1435467-38-1
PubChemID	71568997
InChIKey	LJBUZOGABRDGBR-UHFFFAOYSA-N
Smiles	COC1=CC(C2=CC(NC(N2CC(N)=O)=S)=O)=C(C=C1)OC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	6.43	20mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight321.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.11mL	15.56mL	31.12mL
5mM	0.62mL	3.11mL	6.22mL
10mM	0.31mL	1.56mL	3.11mL
50mM	0.06mL	0.31mL	0.62mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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