Tocris/PF 06447475/5716/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PF 06447475/5716/50/50 mg

Tocris/PF 06447475/5716/50/50 mg

商品编号： 5716/50

品牌： Tocris Bioscience

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:PotentLRRK2inhibitor;neuroprotective

ChemicalName:3-[4-(4-Morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentLRRK2inhibitor(IC₅₀=3nM).Attenuatesα-synuclein-induceddopaminergicneurodegenerationandneuroinflammationinG2019S-LRRK2expressingrats.Alsoneuroprotectiveinwildtyperats.Brainpenetrant.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc

CompoundLibraries

PF06447475isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	305.33
Formula	C₁₇H₁₅N₅O
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1527473-33-1
PubChemID	72706840
InChIKey	BHTWDJBVZQBRKP-UHFFFAOYSA-N
Smiles	N#CC1=CC(C3=CNC2=NC=NC(N4CCOCC4)=C23)=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	15.27	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight305.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.28mL	16.38mL	32.75mL
5mM	0.66mL	3.28mL	6.55mL
10mM	0.33mL	1.64mL	3.28mL
50mM	0.07mL	0.33mL	0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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