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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/PF 3845/4175/50/50毫克
商品详细Tocris/PF 3845/4175/50/50毫克
Tocris/PF 3845/4175/50/50毫克
Tocris/PF 3845/4175/50/50毫克
商品编号: 4175/50
品牌: Tocris Bioscience
市场价: ¥20500.00
美元价: 12300.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:SelectiveFAAHinhibitor
ChemicalName:N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivefattyacidamidehydrolase(FAAH)inhibitor(Ki=0.23μM).ReducesinflammatorypainviaacannABInoidreceptor-dependentmechanism.Highlyefficaciousandselectiveinvivo.DisplaysnoactivityatFAAH-2(IC50>10μM).

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

CompoundLibraries

PF3845isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt456.46
FormulaC24H23F3N4O2
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1196109-52-0
PubChemID25154867
InChIKeyNBOJHRYUGLRASX-UHFFFAOYSA-N
SmilesO=C(NC2=CN=CC=C2)N1CCC(CC3=CC=CC(OC4=NC=C(C(F)(F)F)C=C4)=C3)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.65100
ethanol22.8250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight456.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.19mL10.95mL21.91mL
5mM0.44mL2.19mL4.38mL
10mM0.22mL1.1mL2.19mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet