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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/PF 8380/4078/10/10毫克
商品详细Tocris/PF 8380/4078/10/10毫克
Tocris/PF 8380/4078/10/10毫克
Tocris/PF 8380/4078/10/10毫克
商品编号: 4078/10
品牌: Tocris Bioscience
市场价: ¥3980.00
美元价: 2388.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potentautotaxininhibitor
ChemicalName:3,5-Dichlorobenzyl-[4-[3-oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]]piperazine-1-carboxylate
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentautotaxininhibitor(IC50=2.8nMinisolatedenzymeassay;101nMinhumanwholeblood).Modulateslysophosphatidicacid(LPA)levelsinvivoandinvitrobydirectlyinhibitingautotaxin;reducesLPAlevelsbothinplasmaandatsiteofinflammation.Orallyavailable.

TechnicalData

M.Wt478.33
FormulaC22H21Cl2N3O5
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber1144035-53-9
PubChemID25265312
InChIKeyJMSUDQYHPSNBSN-UHFFFAOYSA-N
SmilesO=C(C2=CC(OC(N4)=O)=C4C=C2)CCN1CCN(C(OCC3=CC(Cl)=CC(Cl)=C3)=O)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO47.83100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight478.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.09mL10.45mL20.91mL
5mM0.42mL2.09mL4.18mL
10mM0.21mL1.05mL2.09mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet