Tocris/PFK 15/5339/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PFK 15/5339/10/10 mg

Tocris/PFK 15/5339/10/10 mg

商品编号： 5339/10

品牌： Tocris Bioscience

市场价： ¥2580.00

美元价： 1548.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectivePFKFB3inhibitor

ChemicalName:1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

OriginallyreportedtobeaselectivePFKFB3inhibitor(IC₅₀=207nM);amorerecentreportfailedtodemonstrateactivityinaPFKFB3kinaseassay.SelectiveforPFKFB3overapanelof96kinases.ReducesglucoseuptakeandinducesapoptosisinH522lungadenocarcinomaandJurkatTcellleukemiacells.Suppressesglucoseuptakeandtumorgrowth,andinhibitsmetastasisofLewislungcarcinomacellxenograftsinmice.

TechnicalData

M.Wt	260.29
Formula	C₁₇H₁₂N₂O
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	4382-63-2
PubChemID	25142799
InChIKey	UJJUKZPBUMCSJZ-BQYQJAHWSA-N
Smiles	O=C(/C=C/C2=CC=C(C=CC=C3)C3=N2)C1=CC=NC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	26.03	100
	ethanol	2.6	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight260.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.84mL	19.21mL	38.42mL
5mM	0.77mL	3.84mL	7.68mL
10mM	0.38mL	1.92mL	3.84mL
50mM	0.08mL	0.38mL	0.77mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

SolubilityData

PreparingStockSolutions

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