Tocris/PH 797804/5866/50/50 mg-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > Other_enzymes > Tocris/PH 797804/5866/50/50 mg

商品详细Tocris/PH 797804/5866/50/50 mg

Tocris/PH 797804/5866/50/50 mg

商品编号： 5866/50

品牌： Tocris Bioscience

市场价： ¥15300.00

美元价： 9180.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:Potentandselectivep38α/βinhibitor

ChemicalName:(-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivep38α/βinhibitor(IC₅₀valuesare26and102nM,respectively).Exhibits>100-foldselectivityforp38α/βover71otherkinases,enzymesandGPCRs,includingp38γ,p38δ,JNKandERK2.InhibitsLPS-inducedTNFαproductioninU937monocytesinvitro.Suppressesacuteandchronicinflammatoryresponsesinratmodelsofarthritis.Orallyactive.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc

TechnicalData

M.Wt	477.3
Formula	C₂₂H₁₉BrF₂N₂O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1358027-80-1
PubChemID	22049997
InChIKey	KCAJXIDMCNPGHZ-UHFFFAOYSA-N
Smiles	FC1=CC=C(COC2=C(Br)C(N(C3=CC(C(NC)=O)=CC=C3C)C(C)=C2)=O)C(F)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	23.86	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight477.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.1mL	10.48mL	20.95mL
5mM	0.42mL	2.1mL	4.19mL
10mM	0.21mL	1.05mL	2.1mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage:

BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets