Tocris/PI 3065/5919/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PI 3065/5919/50/50 mg

Tocris/PI 3065/5919/50/50 mg

商品编号： 5919/50

品牌： Tocris Bioscience

市场价： ¥18100.00

美元价： 10860.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectivePI3-kinasep110δinhibitor

ChemicalName:6-[[4-(Cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-1H-indol-4-yl)-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivePI3-kinasep110δinhibitor(IC₅₀=5nM;K_i=1.5nM).Exhibits>100-foldselectivityoverp100α,p100γandp100βisoforms(IC₅₀valuesare600,910,>10,000nM,respectively).Attenuates4TItumorgrowthandmetastasisinvivo.

TechnicalData

M.Wt	506.64
Formula	C₂₇H₃₁FN₆OS
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	955977-50-1
PubChemID	24937012
InChIKey	YDNOHCOYQVZOMC-UHFFFAOYSA-N
Smiles	FC1=CC=C2NC=CC2=C1C3=NC(N4CCOCC4)=C5SC(CN6CCN(CC6)CC7CC7)=CC5=N3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	10.13	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight506.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.97mL	9.87mL	19.74mL
5mM	0.39mL	1.97mL	3.95mL
10mM	0.2mL	0.99mL	1.97mL
50mM	0.04mL	0.2mL	0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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