Biological Activity
Negative control of IPA 3 (Cat. No. 3622) a direct, non-competitive inhibitor of group I p21-activated kinase (Pak1).
Technical Data
| M. Wt | 350.45 |
| Formula | C20H14O2S2 |
| Storage | Store at +4°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 6088-51-3 |
| PubChem ID | 22463 |
| InChI Key | AHXGXXJEEHFHDK-UHFFFAOYSA-N |
| Smiles | OC1=CC=C2C(C=CC(SSC3=CC(C=CC(O)=C4)=C4C=C3)=C2)=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.28 | 75 | |
| ethanol | 3.5 | 10 |
Preparing Stock Solutions
The following data is based on the product molecular weight 350.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.85 mL | 14.27 mL | 28.53 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.71 mL |
| 10 mM | 0.29 mL | 1.43 mL | 2.85 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.57 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Deacon et al (2008) An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem.Biol. 15 322 PMID: 18420139
Keywords: PIR 3.5, supplier, PIR, 3.5, PIR3.5, negative, control, IPA-3, inhibits, Pak1, inhibitors, P21-activated, Kinases, P21-activated, Kinases, Tocris Bioscience
