Biological Activity
Inactive control for PKC (19-36) (Cat. No. 4058), a pseudosubstrate peptide inhibitor of protein kinase C.
Technical Data
M. Wt | 2124.43 |
Formula | C92H154N32O26 |
Sequence | RFARKGALEQKNVHEVKN |
Storage | Store at -20°C |
CAS Number | 309247-49-2 |
PubChem ID | 90488906 |
InChI Key | MGMBDJURDVUJCE-KHVJKNDMSA-N |
Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solubility | Soluble to 1 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 2124.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 0.47 mL | 2.35 mL | 4.71 mL |
5 mM | 0.09 mL | 0.47 mL | 0.94 mL |
10 mM | 0.05 mL | 0.24 mL | 0.47 mL |
50 mM | 0.01 mL | 0.05 mL | 0.09 mL |
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References
References are publications that support the products' biological activity.
Yasunari et al (1996) Possible involvement of phospholipase D and protein kinase C in vascular growth induced by elevated glucose concentration. Hypertension 28 159 PMID: 8707376
Keywords: [Glu27]-PKC (19-36), supplier, Inactive, control, peptides, PKC, (19-36), protein, kinase, c, inhibitors, inhibits, pkc, Protein, Kinase, C, Protein, Kinase, C, Tocris Bioscience