Biological Activity
Potent and selective α1-adrenoceptor antagonist and antihypertensive.
Technical Data
| M. Wt | 361.45 |
| Formula | C21H23N5O |
| Storage | Store at RT |
| CAS Number | 139047-55-5 |
| PubChem ID | 6081682 |
| InChI Key | ONSOQRPYFKDOEB-UHFFFAOYSA-N |
| Smiles | O=C1NC2=C(C=CC=C2)C2=NC(CN3CCN(CC3)C3=CC=CC=C3)CN12 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 3.61 | 10 | |
| ethanol | 0 |
Preparing Stock Solutions
The following data is based on the product molecular weight 361.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.77 mL | 13.83 mL | 27.67 mL |
| 5 mM | 0.55 mL | 2.77 mL | 5.53 mL |
| 10 mM | 0.28 mL | 1.38 mL | 2.77 mL |
| 50 mM | 0.06 mL | 0.28 mL | 0.55 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
on-line. Please contact Customer Service
References
References are publications that support the products' biological activity.
Chern et al (1993) Studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives - a novel class of potent and selective α1-adrenoceptor antagonists and antihypertensive agents. J.Med.Chem. 36 2196 PMID: 8101878
Keywords: 2-PMDQ, supplier, Potent, selective, α1-adrenoceptor, alpha1-adrenoceptor, α1-adrenergic, alpha1-adrenergic, a1-adrenergic, a1-adrenoceptor, antagonists, receptors, antihypertensive, Adrenergic, Alpha-1, Receptors, Adrenergic, Alpha-1, Receptors, Tocris Bioscience
