Tocris/PNU 282987/2303/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/PNU 282987/2303/10/10 mg

Tocris/PNU 282987/2303/10/10 mg

商品编号： 2303/10

品牌： Tocris Bioscience

市场价： ¥2980.00

美元价： 1788.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Selectiveα7nAChRagoNIST

ChemicalName:N-(3R)-1-AzABIcyclo[2.2.2]oct-3-yl-4-chlorobenzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highlyselectiveα7nAChRagonist(K_i=26nM)displayingnegligIBLeblockadeofα₁β₁γδandα₃β₄nAChRs(IC₅₀≥60μM).Foundtobeinactiveagainstapanelof32receptorsat1μM,except5-HT₃receptors(K_i=930nM).

CompoundLibraries

PNU282987isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	264.75
Formula	C₁₄H₁₇ClN₂O
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	123464-89-1
PubChemID	9795278
InChIKey	WECKJONDRAUFDD-ZDUSSCGKSA-N
Smiles	O=C(C2=CC=C(Cl)C=C2)N[C@@H]1C3CCN(CC3)C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	26.48	100
	DMSO	26.48	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight264.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.78mL	18.89mL	37.77mL
5mM	0.76mL	3.78mL	7.55mL
10mM	0.38mL	1.89mL	3.78mL
50mM	0.08mL	0.38mL	0.76mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets