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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/PP 1/1397/10/10 mg
商品详细Tocris/PP 1/1397/10/10 mg
Tocris/PP 1/1397/10/10 mg
Tocris/PP 1/1397/10/10 mg
商品编号: 1397/10
品牌: Tocris Bioscience
市场价: ¥4980.00
美元价: 2988.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potent,selectiveSrcfamilykinaseinhibitor
ChemicalName:1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitorofSrc-familytyrosinekinases.Inhibitsp56lckandp59fynT(IC50valuesare5and6nMrespectively).Displays>8000-foldselectivityoverZAP-70andJAK2.Alsomoderatelyinhibitsp38,CSK,PDGFreceptors,RET-derivedoncoproteins,c-KitandBcr-Abl.

TechnicalData

M.Wt281.36
FormulaC16H19N5
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber172889-26-8
PubChemID1400
InChIKeyZVPDNRVYHLRXLX-UHFFFAOYSA-N
SmilesCC1=CC=C(C=C1)C1=NN(C2=NC=NC(N)=C12)C(C)(C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto10mMinDMSOandto10mMinethanol

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight281.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.55mL17.77mL35.54mL
5mM0.71mL3.55mL7.11mL
10mM0.36mL1.78mL3.55mL
50mM0.07mL0.36mL0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet