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当前位置: 首页 > 产品中心 > kinase > Tocris/PQ 401/2768/10/10毫克
商品详细Tocris/PQ 401/2768/10/10毫克
Tocris/PQ 401/2768/10/10毫克
Tocris/PQ 401/2768/10/10毫克
商品编号: 2768/10
品牌: Tocris Bioscience
市场价: ¥2980.00
美元价: 1788.00
产地: 美国(厂家直采)
公司:
产品分类: 激酶
公司分类: kinase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:IGF1Rinhibitor
ChemicalName:N-(5-Chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)urea
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Insulin-likegrowthfactorreceptor(IGF1R)inhibitor.SuppressesIGF-stimulatedIGF-IRautophosphorylationwithanIC50valueof12μM.InhibitsgrowthofMCF-7breastcancercellsinvitroandinvivo.

CompoundLibraries

PQ401isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxI.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt341.79
FormulaC18H16ClN3O2
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber196868-63-0
PubChemID9549305
InChIKeyYBLWOZUPHDKFOT-UHFFFAOYSA-N
SmilesO=C(NC3=C(OC)C=CC(Cl)=C3)NC2=CC(C)=NC1=CC=CC=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO17.0950
ethanol8.5425

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight341.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.93mL14.63mL29.26mL
5mM0.59mL2.93mL5.85mL
10mM0.29mL1.46mL2.93mL
50mM0.06mL0.29mL0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet