Biological Activity
Potent, selective P2Y2 agonist (EC50 = 0.134 μM). Displays >60-fold selectivity versus P2Y4 and P2Y6 receptors.
Technical Data
| M. Wt | 622.14 |
| Formula | C10H11F2N2Na4O13P3S |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1657025-60-9 |
| PubChem ID | 90488930 |
| InChI Key | KATPYMNMKKBLAH-GENVZAMMSA-J |
| Smiles | [Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)C(O[C@@H]1COP([O-])(=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O)N1C=CC(=S)NC1=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
Preparing Stock Solutions
The following data is based on the product molecular weight 622.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.61 mL | 8.04 mL | 16.07 mL |
| 5 mM | 0.32 mL | 1.61 mL | 3.21 mL |
| 10 mM | 0.16 mL | 0.8 mL | 1.61 mL |
| 50 mM | 0.03 mL | 0.16 mL | 0.32 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
El-Tayeb et al (2011) Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. J.Med.Chem. 54 2878 PMID: 21417463
Keywords: PSB 1114, supplier, PSB1114, P2Y2, receptors, agonist, purinergic, P2Y, 2, agonists, purinoceptors, Purinergic, P2Y, Receptors, Purinergic, P2Y, Receptors, Tocris Bioscience
