Biological Activity
Inhibitor of release of dopamine induced by methamphetamine.
Technical Data
M. Wt | 245.75 |
Formula | C15H15N.HCl |
Storage | Store at RT |
CAS Number | 6109-35-9 |
PubChem ID | 12999296 |
InChI Key | YYCOJKPDBCMVPP-UHFFFAOYSA-N |
Smiles | Cl.C1NCC2=C(C=CC=C2)C1C1=CC=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
water | 6.14 | 25 |
Preparing Stock Solutions
The following data is based on the product molecular weight 245.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 4.07 mL | 20.35 mL | 40.69 mL |
5 mM | 0.81 mL | 4.07 mL | 8.14 mL |
10 mM | 0.41 mL | 2.03 mL | 4.07 mL |
50 mM | 0.08 mL | 0.41 mL | 0.81 mL |
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References
References are publications that support the products' biological activity.
Tateyama et al (1993) 4-Phenyltetrahydroisoquinoline, but not nomifensine or cocaine, inhibits methamphetamine-induced dopamine release. Eur.J.Pharmacol. 240 51 PMID: 8405121
Keywords: 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride, supplier, DA, release, inhibitors, inhibits, Dopaminergic, Dopamine, Receptors, Dopaminergic-Related, Dopaminergic-Related, Tocris Bioscience