![Tocris/2-[1-(4-Piperonyl)piperazinyl]benzothiazole/0736/10/10 mg](https://www.ebiomall.cn/images/201712/1512520182640885781.jpg)
Biological Activity
5-HT4 receptor agonist with moderate activity as a 5-HT3 antagonist. Has no affinity at 5-HT1 or dopamine D2 receptors. Potential gastrokinetic agent.
Technical Data
| M. Wt | 353.44 |
| Formula | C19H19N3O2S |
| Storage | Store at RT |
| CAS Number | 155106-73-3 |
| PubChem ID | 127902 |
| InChI Key | BYHKGNWKJMGHGE-UHFFFAOYSA-N |
| Smiles | C(N1CCN(CC1)C1=NC2=CC=CC=C2S1)C1=CC2=C(OCO2)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 3.53 | 10mM with gentle warming |
Preparing Stock Solutions
The following data is based on the product molecular weight 353.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.83 mL | 14.15 mL | 28.29 mL |
| 5 mM | 0.57 mL | 2.83 mL | 5.66 mL |
| 10 mM | 0.28 mL | 1.41 mL | 2.83 mL |
| 50 mM | 0.06 mL | 0.28 mL | 0.57 mL |
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Product Datasheets
on-line. Please contact Customer Service
References
References are publications that support the products' biological activity.
Monge et al (1994) Synthesis of 2-piperazinybenzothiazole and 2-piperazinylbenzoxazole derivatives with 5-HT3 antagonist and 5-HT4 agonist properties. J.Med.Chem. 37 1320 PMID: 8176710
Keywords: 2-[1-(4-Piperonyl)piperazinyl]benzothiazole, supplier, 5-HT4, agonists, 5-HT3, antagonists, Serotonin, Receptors, 5-Hydroxytryptamine, 5-HT, 5-HT4, Receptors, 5-HT4, Receptors, Tocris Bioscience
