Biological Activity
Nootropic that displays cognitive enhancing properties. Proposed to enhance neurotransmission via modulation of ion flux; potentiates Na+ influx through AMPA receptors. Facilitates efficiency of cholinergic neurotransmission at muscarinic receptors.
Technical Data
| M. Wt | 142.16 |
| Formula | C6H10N2O2 |
| Storage | Store at RT |
| CAS Number | 7491-74-9 |
| PubChem ID | 4843 |
| InChI Key | GMZVRMREEHBGGF-UHFFFAOYSA-N |
| Smiles | O=C1CCCN1CC(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 14.22 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 142.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 7.03 mL | 35.17 mL | 70.34 mL |
| 5 mM | 1.41 mL | 7.03 mL | 14.07 mL |
| 10 mM | 0.7 mL | 3.52 mL | 7.03 mL |
| 50 mM | 0.14 mL | 0.7 mL | 1.41 mL |
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References
References are publications that support the products' biological activity.
Vernon and Sorkin (1991) Piracetam. An overview of its pharmacological properties and a review of its therapeutic use in senile cognitive disorders. Drugs Aging. 1 17 PMID: 1794001
Gouliaev and Senning (1994) Piracetam and other structurally related nootropics. Brain Res.Brain Res.Rev. 19 180 PMID: 8061686
Winbald (2005) Piracetam: a review of pharmacological properties and clinical uses. CNS Drug Rev. 11 169 PMID: 16007238
Keywords: Piracetam, supplier, Nootropic, modulates, Na+-flux, AMPA, receptors, Modulates, neurotransmission, Glutamate, Receptors, iGluR, Ionotropic, Muscarinic, Acetylcholine, ACh, AMPA, Receptors, Non-selective, Muscarinics, AMPA, Receptors, Tocris Bioscience
