Biological Activity
β-adrenergic antagonist, clinically effective in the treatment of angina pectoris and some arrhythmias.
Licensing Information
Sold with the permission of AstraZeneca UK Ltd.
Technical Data
| M. Wt | 265.78 |
| Formula | C15H19NO.HCl |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 51-02-5 |
| PubChem ID | 60975 |
| InChI Key | QONLGXRPRAIDGI-UHFFFAOYSA-N |
| Smiles | Cl.CC(C)NCC(O)C1=CC=C2C=CC=CC2=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 265.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.76 mL | 18.81 mL | 37.63 mL |
| 5 mM | 0.75 mL | 3.76 mL | 7.53 mL |
| 10 mM | 0.38 mL | 1.88 mL | 3.76 mL |
| 50 mM | 0.08 mL | 0.38 mL | 0.75 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Main (1990) α-Adrenergic receptors. Comprehensive Medicinal Chemistry. Ed Hansch 3 187 PMID:
Merck Index 12 7974 PMID:
Keywords: Pronethalol hydrochloride, supplier, β-adrenoceptor, beta-adrenoceptors, β-adrenergic, beta-adrenergic, b-adrenoceptors, b-adrenergic, antagonists, Receptors, Non-Selective, ICI38174, AstraZeneca, ICI-38174, Non-selective, Adrenergic, Beta, Receptors, Non-selective, Adrenergic, Beta, Receptors, Tocris Bioscience
