Biological Activity
Sodium channel blocker.
Technical Data
M. Wt | 256.77 |
Formula | C13H21ClN2O |
Storage | Desiccate at RT |
CAS Number | 5369-00-6 |
PubChem ID | 9795082 |
InChI Key | WFKXSWWTOZBDME-UHFFFAOYSA-N |
Smiles | [Cl-].CC1=CC=CC(C)=C1NC(=O)C[N+](C)(C)C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 256.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 3.89 mL | 19.47 mL | 38.95 mL |
5 mM | 0.78 mL | 3.89 mL | 7.79 mL |
10 mM | 0.39 mL | 1.95 mL | 3.89 mL |
50 mM | 0.08 mL | 0.39 mL | 0.78 mL |
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References
References are publications that support the products' biological activity.
Cuevas and Adams (1994) Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat parasympathetic ganglion cells. Br.J.Pharmacol. 11 663 PMID: 7517326
Hanck et al (1994) Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. J.Gen.Physiol. 103 19 PMID: 8169596
Keywords: QX 222, supplier, Na+, channel, blockers, Sodium, NaV, Channels, voltage-gated, voltage-dependent, QX222, Voltage-gated, Sodium, Channels, Voltage-gated, Sodium, Channels, Tocris Bioscience