Tocris/R 59-022/2194/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/R 59-022/2194/50/50毫克

Tocris/R 59-022/2194/50/50毫克

商品编号： 2194/50

品牌： Tocris Bioscience

市场价： ¥11700.00

美元价： 7020.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Diacylglycerolkinaseinhibitor;increasesPKCactivity

ChemicalName:6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Diacylglycerol(DAG)kinaseinhibitor(IC₅₀=2.8μM);increasesproteinkinaseCactivity.Potentiatesthrombin-inducedplateletaggregationandinducesneutrophilchemotaxis.InhibitsU46619-inducedcontractionsinmouseaortaandporcinecoronaryartery.

CompoundLibraries

R59-022isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	459.58
Formula	C₂₇H₂₆FN₃OS
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	93076-89-2
PubChemID	3012
InChIKey	MFVJXLPANKSLLD-UHFFFAOYSA-N
Smiles	CC1=C(CCN2CCC(CC2)=C(/C2=CC=CC=C2)C2=CC=C(F)C=C2)C(=O)N2C=CSC2=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	22.98	50
	ethanol	9.19	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight459.58.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.18mL	10.88mL	21.76mL
5mM	0.44mL	2.18mL	4.35mL
10mM	0.22mL	1.09mL	2.18mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets