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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/RJR 2429 dihydrochloride/1271/10/10 mg
商品详细Tocris/RJR 2429 dihydrochloride/1271/10/10 mg
Tocris/RJR 2429 dihydrochloride/1271/10/10 mg
Tocris/RJR 2429 dihydrochloride/1271/10/10 mg
商品编号: 1271/10
品牌: Tocris Bioscience
市场价: ¥3100.00
美元价: 1860.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:NicotinicreceptoragoNIST
ChemicalName:(±)-2-(3-Pyridinyl)-1-azABIcyclo[2.2.2]octanedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentnAChRagonistthatdisplaysselectivityforα4β2(Ki=1nM)andα1βγδsubtypes(EC50valuesare297and55nMrespectively).Inducesdopaminereleasefromstriatalneurons(EC50=2nM)andinhibitsionfluxinthalamicneurons(IC50=154nM).Alsoputativeα3β4agonistthatpotentiatescatecholaminerelease.

TechnicalData

M.Wt261.19
FormulaC12H16N2.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber1021418-53-0
PubChemID56972204
InChIKeyPIUNXHHZRIUBOV-UHFFFAOYSA-N
SmilesC1(C2N3CCC(CC3)C2)=CC=CN=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.12100
water26.12100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight261.19.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.83mL19.14mL38.29mL
5mM0.77mL3.83mL7.66mL
10mM0.38mL1.91mL3.83mL
50mM0.08mL0.38mL0.77mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet