Tocris/RN 1二盐酸盐/4977/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/RN 1二盐酸盐/4977/10/10 mg

Tocris/RN 1二盐酸盐/4977/10/10 mg

商品编号： 4977/10

品牌： Tocris Bioscience

市场价： ¥3900.00

美元价： 2340.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:LSD1inhibitor

ChemicalName:1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanonedihydrochloride

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentlysinespecificdemethylase1(LSD1)inhibitor(IC₅₀=70nM).ExhibitsselectivityforLSD1overMAO-AandMAO-B(IC₅₀valuesare0.51and2.79μMforMAO-AandMAO-B,respectively).Impairslong-term,butnotshort-termmemoryinmice.BrainpenetrantfollowingsystemicadmiNISTration.

CompoundLibraries

RN1dihydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	452.42
Formula	C₂₃H₂₉N₃O₂.2HCl
Storage	Storeat-20°C
Purity	≥97%(HPLC)
CASNumber	1781835-13-9
PubChemID	90488995
InChIKey	WMHAFZOOUBPQRX-VSIGASKDSA-N
Smiles	O=C(N4CCN(C)CC4)CN[C@@H]1C[C@H]1[C@]2=CC=C(OCC3=CC=CC=C3)C=C2.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	9.05	20mMwithgentlewarming
	water	9.05	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight452.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.21mL	11.05mL	22.1mL
5mM	0.44mL	2.21mL	4.42mL
10mM	0.22mL	1.11mL	2.21mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets