Tocris/RN 1734/3746/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/RN 1734/3746/50/50 mg

Tocris/RN 1734/3746/50/50 mg

商品编号： 3746/50

品牌： Tocris Bioscience

市场价： ¥10700.00

美元价： 6420.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveTRPV4antagoNIST

ChemicalName:2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveTRPV4antagonist(IC₅₀valuesare2.3,3.2and5.9μMforhTRPV4,rTRPV4andmTRPV4receptorsrespectively).DisplaysselectivityforTRPV4overotherTRPchannels(IC₅₀valuesare2.3,>30,>30and>100μMforTRPV4,TRPV3,TRPM8andTRPV1respectively).BlocksTRPV4-mediatedarteriolevasodilationandincreasesmyogenictoneexvivo.

CompoundLibraries

RN1734isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	353.31
Formula	C₁₄H₂₂Cl₂N₂O₂S
Storage	Storeat+4°C
CASNumber	946387-07-1
PubChemID	3601086
InChIKey	IHYZMEAZAIFMTN-UHFFFAOYSA-N
Smiles	CC(C)NCCN(C(C)C)S(C1=C(Cl)C=C(Cl)C=C1)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	35.33	100
	ethanol	17.67	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight353.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.83mL	14.15mL	28.3mL
5mM	0.57mL	2.83mL	5.66mL
10mM	0.28mL	1.42mL	2.83mL
50mM	0.06mL	0.28mL	0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

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ProductDatasheets