Tocris/RO-3/3052/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/RO-3/3052/10/10 mg

Tocris/RO-3/3052/10/10 mg

商品编号： 3052/10

品牌： Tocris Bioscience

市场价： ¥3180.00

美元价： 1908.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveP2X₃andP2X_2/3antagoNIST

ChemicalName:5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivehomomericP2X₃andheteromericP2X_2/3receptorantagonist(pIC₅₀valuesare7.0and5.9respectively)thatexhibitsnoactivityatP2X₁,P2X₂,P2X₄,P2X₅andP2X₇receptors(IC₅₀>10μM).Attenuatesnociceptivesensitivityinanimalmodelsofpain.Orallyactiveandbrainpenetrant.

CompoundLibraries

RO-3isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	302.37
Formula	C₁₆H₂₂N₄O₂
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	1026582-88-6
PubChemID	11289644
InChIKey	PYNPWUIBJMVRIG-UHFFFAOYSA-N
Smiles	NC1=NC(N)=NC=C1CC2=C(C(C)C)C=C(OC)C(OC)=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	30.24	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight302.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.31mL	16.54mL	33.07mL
5mM	0.66mL	3.31mL	6.61mL
10mM	0.33mL	1.65mL	3.31mL
50mM	0.07mL	0.33mL	0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

DilutionCalculator

ProductDatasheets