Biological Activity
A high affinity, selective competitive antagonist at 5-HT4 receptors.
Licensing Information
Sold with the permission of Roche Bioscience
Technical Data
| M. Wt | 363.28 |
| Formula | C16H23ClN2O3.HCl |
| Storage | Store at RT |
| CAS Number | 149719-06-2 |
| PubChem ID | 182592 |
| InChI Key | QLZLBYYNMGQIAR-UHFFFAOYSA-N |
| Smiles | Cl.COC1=CC(N)=C(Cl)C=C1C(=O)OCCCN1CCCCC1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 363.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.75 mL | 13.76 mL | 27.53 mL |
| 5 mM | 0.55 mL | 2.75 mL | 5.51 mL |
| 10 mM | 0.28 mL | 1.38 mL | 2.75 mL |
| 50 mM | 0.06 mL | 0.28 mL | 0.55 mL |
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Product Datasheets
on-line. Please contact Customer Service
References
References are publications that support the products' biological activity.
Eglen et al (1993) RS 23597-190: a potent and selective 5-HT4 receptor antagonist. Br.J.Pharmacol. 110 119 PMID: 8220871
Eglen et al (1995) Central 5-HT4 receptors. TiPS 16 391 PMID: 8578609
Keywords: RS 23597-190 hydrochloride, supplier, 5-HT4, antagonists, Serotonin, Receptors, 5-Hydroxytryptamine, 5-HT, RS23597-190, hydrochloride, 5-HT4, Receptors, 5-HT4, Receptors, Tocris Bioscience
