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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/RS 25344 hydrochloride/3315/50/50 mg
商品详细Tocris/RS 25344 hydrochloride/3315/50/50 mg
Tocris/RS 25344 hydrochloride/3315/50/50 mg
Tocris/RS 25344 hydrochloride/3315/50/50 mg
商品编号: 3315/50
品牌: Tocris Bioscience
市场价: ¥13300.00
美元价: 7980.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentPDE4inhibitor
ChemicalName:1-(3-Nitrophenyl)-3-(4-pyridinylmethyl)-pyrido[2,3-d]pyrimidine-2,3-(1H,3H)-dionehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivephosphodiesterase(PDE)4inhibitor(IC50valuesare0.28,>100,160and330nMatPDE4,PDE1,PDE2andPDE3respectively).Inhibitseosinophilchemotaxisandincreasesprogressivemotilityofspermatozoainvitro.

TechnicalData

M.Wt411.8
FormulaC19H13N5O4.HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber152815-28-6
PubChemID19781728
InChIKeyROSFKXDQMBPYQQ-UHFFFAOYSA-N
SmilesO=C(N(CC4=CC=NC=C4)C2=O)N(C3=CC([N+]([O-])=O)=CC=C3)C1=C2C=CC=N1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.18100
water20.5950

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight411.8.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.43mL12.14mL24.28mL
5mM0.49mL2.43mL4.86mL
10mM0.24mL1.21mL2.43mL
50mM0.05mL0.24mL0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet