Biological Activity
Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221); comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction.
Technical Data
| M. Wt | 1632.89 |
| Formula | C72H116N18O23S |
| Sequence | MVDGKPVNLGLFDTAG |
| Storage | Desiccate at -20°C |
| CAS Number | 1315378-77-8 |
| PubChem ID | 90488751 |
| InChI Key | DYGBZJOTQUWNJM-BHRKYZIESA-N |
| Smiles | [H]N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NCC(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 1 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 1632.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.61 mL | 3.06 mL | 6.12 mL |
| 5 mM | 0.12 mL | 0.61 mL | 1.22 mL |
| 10 mM | 0.06 mL | 0.31 mL | 0.61 mL |
| 50 mM | 0.01 mL | 0.06 mL | 0.12 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Gao et al (2001) Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors. J.Biol.Chem. 276 47530 PMID: 11595749
Keywords: Rac1 Inhibitor F56, control peptide, supplier, Control, peptide, version, Rac1, inhibitors, inhibits, W56, G, Proteins, Small, GTPases, G, Proteins, (Small), GTPase, G, Proteins, (Small), Tocris Bioscience
