4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/Ro 106-9920/1778/50/50 mg
商品详细Tocris/Ro 106-9920/1778/50/50 mg
Tocris/Ro 106-9920/1778/50/50 mg
Tocris/Ro 106-9920/1778/50/50 mg
商品编号: 1778/50
品牌: Tocris Bioscience
市场价: ¥11700.00
美元价: 7020.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:InhibitorofNF-κBactivation
ChemicalName:6-(Phenylsulfinyl)tetrazolo[1,5-b]pyridazine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofNF-κBactivation,possIBLyviaselectiveinhibitionofLPS-andTNF-α-inducedIκBαubiquitination(IC50=3μM).BlockssubsequentproductionofTNF-α,IL-1βandIL-6.InhibitsmucinproductioninaninvitromodelofCOPD,andisanti-inflammatoryfollowingoraladmiNISTrationinvivo.AlsoweaklyinhibitsEGFR,5-lipoxygenaseandiNOS.

CompoundLibraries

Ro106-9920isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt245.26
FormulaC10H7N5OS
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber62645-28-7
PubChemID3906779
InChIKeyJFSXSNSCPNFCDM-UHFFFAOYSA-N
SmilesO=S(C1=CC=CC=C1)C1=NN2N=NN=C2C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.53100
ethanol1.235

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight245.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.08mL20.39mL40.77mL
5mM0.82mL4.08mL8.15mL
10mM0.41mL2.04mL4.08mL
50mM0.08mL0.41mL0.82mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet