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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Lipid_metabolism_study > Tocris/Ro 48-8071富马酸盐/5389/50/50毫克
商品详细Tocris/Ro 48-8071富马酸盐/5389/50/50毫克
Tocris/Ro 48-8071富马酸盐/5389/50/50毫克
Tocris/Ro 48-8071富马酸盐/5389/50/50毫克
商品编号: 5389/50
品牌: Tocris Bioscience
市场价: ¥7180.00
美元价: 4308.00
产地: 美国(厂家直采)
公司:
产品分类: 脂质代谢研究
公司分类: Lipid_metabolism_study
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:2,3-Oxidosqualenecyclase(OSC)inhibitor;blockscholesterolsynthesis
ChemicalName:(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

2,3-Oxidosqualenecyclase(OSC)inhibitor(IC50=6.5nM);blockscholesterolsynthesisinHepG2cells.ReducesviABIlityofbreastcancercelllines.AlsoinhibitsEbolavirus(EBOV)cellentry(IC50=1.74μM).

CompoundLibraries

Ro48-8071fumarateisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt564.44
FormulaC23H27BrFNO2.C4H4O4
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber189197-69-1
PubChemID9959583
InChIKeyXCYAYLWZCRGKDS-WLHGVMLRSA-N
SmilesFC1=C(C(C2=CC=C(Br)C=C2)=O)C=CC(OCCCCCCN(C)CC=C)=C1.OC(/C=C/C(O)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO56.44100
water11.2920mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight564.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.77mL8.86mL17.72mL
5mM0.35mL1.77mL3.54mL
10mM0.18mL0.89mL1.77mL
50mM0.04mL0.18mL0.35mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet