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Tocris Bioscience(优势品牌)
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4000-520-616
当前位置: 首页 > 产品中心 > Receptors > Tocris/SA 4503 dihydrochloride/4951/10/10 mg
商品详细Tocris/SA 4503 dihydrochloride/4951/10/10 mg
Tocris/SA 4503 dihydrochloride/4951/10/10 mg
Tocris/SA 4503 dihydrochloride/4951/10/10 mg
商品编号: 4951/10
品牌: Tocris Bioscience
市场价: ¥3300.00
美元价: 1980.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Selectiveσ1receptoragoNIST
ChemicalName:1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)-piperazinedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveσ1receptoragonist(IC50=17.4nM).Exhibitsselectivityforσ1overσ2receptors.InhibitsangiotensinII-inducedcardiomyocytehypertrophyinvitroandattenuatesmyocardialhypertrophyinvivo.Enhancesbrainplasticityandsensorimotorfunctioninaratmodelofexperimentalstroke.

CompoundLibraries

SA4503dihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt441.43
FormulaC23H32N2O2.2HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber165377-44-6
PubChemID9954941
InChIKeyXWOXAKBQEMQMFH-UHFFFAOYSA-N
SmilesCOC1=C(OC)C=CC(CCN2CCN(CCCC3=CC=CC=C3)CC2)=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO8.8320
water44.14100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight441.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.27mL11.33mL22.65mL
5mM0.45mL2.27mL4.53mL
10mM0.23mL1.13mL2.27mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet