Tocris/SB 203580 hydrochloride/1402/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/SB 203580 hydrochloride/1402/10/10 mg

Tocris/SB 203580 hydrochloride/1402/10/10 mg

商品编号： 1402/10

品牌： Tocris Bioscience

市场价： ¥5180.00

美元价： 3108.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Selectiveinhibitorofp38MAPK;water-soluble

ChemicalName:4-[5-(4-Fluorophenyl)-2-[4-(methylsulphonyl)phenyl]-1H-imidazol-4-yl]pyridinehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Water-solublesaltofSB203580(Cat.No.1202).Selectiveinhibitorofp38mitogen-activatedproteinkinase(IC₅₀valuesare50and500nMforSAPK2a/p38andSAPK2b/p38β2respectively).Displays100-500-foldselectivityoverLCK,GSK3βandPKBα.Showntoinhibitinterleukin-2-inducedTcellproliferation,cyclooxygenase-1and-2,andthromboxanesynthase.

LicensingInformation

SoldwiththepermissionofGlaxoSmithKline

TechnicalData

M.Wt	413.89
Formula	C₂₁H₁₆FN₃OS.HCl
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	869185-85-3
PubChemID	16760644
InChIKey	WOSGGXINSLMASH-UHFFFAOYSA-N
Smiles	Cl.CS(=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=NC=C1)C1=CC=C(F)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	10.35	25mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight413.89.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.42mL	12.08mL	24.16mL
5mM	0.48mL	2.42mL	4.83mL
10mM	0.24mL	1.21mL	2.42mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

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