Tocris/SB 269970盐酸盐/1612/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/SB 269970盐酸盐/1612/50/50 mg

Tocris/SB 269970盐酸盐/1612/50/50 mg

商品编号： 1612/50

品牌： Tocris Bioscience

市场价： ¥16500.00

美元价： 9900.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:Potentandselective5-HT₇antagoNIST;brainpenetrant

ChemicalName:(2R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidinehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselective5-HT₇receptorantagonist(pK_ivaluesare8.9,7.2and6.0for5-HT_7A,5-HT_5Aand5-HT_1Band<6.0for5-HT_1A,5-HT_1D,5-HT_1E,5-HT_1F,5-HT_2A,5-HT_2B,5-HT_2C,5-HT₄and5-HT₆receptorsrespectively).Brainpenetrantinvivo.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline.

CompoundLibraries

SB269970hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	388.95
Formula	C₁₈H₂₈N₂O₃S.HCl
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	261901-57-9
PubChemID	11957684
InChIKey	XQCJOYZLWFNDIO-PKLMIRHRSA-N
Smiles	OC1=CC(S(N2[C@@H](CCN3CCC(C)CC3)CCC2)(=O)=O)=CC=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	phosphatebufferedsaline	1.76	5
	DMSO	38.89	100
	water	7.78	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight388.95.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.57mL	12.86mL	25.71mL
5mM	0.51mL	2.57mL	5.14mL
10mM	0.26mL	1.29mL	2.57mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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