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Tocris Bioscience(优势品牌)
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4000-520-616
当前位置: 首页 > 产品中心 > Receptors > Tocris/SB 328437/3650/50/50毫克
商品详细Tocris/SB 328437/3650/50/50毫克
Tocris/SB 328437/3650/50/50毫克
Tocris/SB 328437/3650/50/50毫克
商品编号: 3650/50
品牌: Tocris Bioscience
市场价: ¥14100.00
美元价: 8460.00
产地: 美国(厂家直采)
公司:
产品分类: 受体
公司分类: Receptors
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentandselectiveCCR3antagoNIST
ChemicalName:N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalaninemethylester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveCCR3antagonist(IC50=4nM).Displays>2500-foldselectivityoverC5aR,LTD4,CCR7,CXCR1andCXCR2receptors.Inhibitseotaxin-,eotaxin-2-andMCP-4-inducedCa2+mobilization(IC50valuesare38,35and20nMrespectively)andinhibitseotaxin-,eotaxin-2-andMCP-4-inducedeosinophilchemotaxiswithsimilarpotencies.

CompoundLibraries

SB328437isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt378.38
FormulaC21H18N2O5
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber247580-43-4
PubChemID10474776
InChIKeyVMFGCGRAIBLAFY-IBGZPJMESA-N
SmilesO=C(C2=CC=CC3=C2C=CC=C3)N[C@H](C(OC)=O)CC1=CC=C([N+]([O-])=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.84100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight378.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.64mL13.21mL26.43mL
5mM0.53mL2.64mL5.29mL
10mM0.26mL1.32mL2.64mL
50mM0.05mL0.26mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet