Tocris/SB 332235/5671/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/SB 332235/5671/10/10 mg

Tocris/SB 332235/5671/10/10 mg

商品编号： 5671/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentCXCR2antagoNIST

ChemicalName:6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentCXCR2antagonist(IC₅₀=7.7nM).Exhibits285-foldselectivityforCXCR2overCXCR1.Reducesleukocytenumbersinsynovialfluidinacuteandchronicrabbitarthritismodels.Alsoreducessynovialfluideicosanoidandcytokinelevelsinarabbitchronicarthritismodel.InhibitsproliferationofAMLcelllinesinvitro.

TechnicalData

M.Wt	410.66
Formula	C₁₃H₁₀Cl₃N₃O₄S
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	276702-15-9
PubChemID	9887803
InChIKey	WTLRWOHEKQGKDS-UHFFFAOYSA-N
Smiles	ClC1=C(S(=O)(N)=O)C(O)=C(NC(NC2=C(Cl)C(Cl)=CC=C2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	41.07	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight410.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.44mL	12.18mL	24.35mL
5mM	0.49mL	2.44mL	4.87mL
10mM	0.24mL	1.22mL	2.44mL
50mM	0.05mL	0.24mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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