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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/SC 560/1550/10/10 mg
商品详细Tocris/SC 560/1550/10/10 mg
Tocris/SC 560/1550/10/10 mg
Tocris/SC 560/1550/10/10 mg
商品编号: 1550/10
品牌: Tocris Bioscience
市场价: ¥3180.00
美元价: 1908.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Cyclooxygenase-1(COX-1)inhibitor
ChemicalName:5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highlyselectivecyclooxygenase-1(COX-1)inhibitor(IC50valuesare0.009and6.3μMforCOX-1andCOX-2respectively).InhibitsCOX-1-derivedplateletthromboxaneB2,gastricPGE2anddermalPDE2production.Significantlyreducesovariansurfaceepithelialtumorgrowthinvivo.Orallyactive.

CompoundLibraries

SC560isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt352.74
FormulaC17H12ClF3N2O
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber188817-13-2
PubChemID4306515
InChIKeyPQUGCKBLVKJMNT-UHFFFAOYSA-N
SmilesCOC1=CC=C(C=C1)N1N=C(C=C1C1=CC=C(Cl)C=C1)C(F)(F)F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.27100
ethanol8.8225

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight352.74.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.83mL14.17mL28.35mL
5mM0.57mL2.83mL5.67mL
10mM0.28mL1.42mL2.83mL
50mM0.06mL0.28mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet