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商品详细Tocris/SI-2 hydrochloride/5964/50/50 mg

Tocris/SI-2 hydrochloride/5964/50/50 mg

商品编号： 5964/50

品牌： Tocris Bioscience

市场价： ¥13900.00

美元价： 8340.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Steroidreceptorcoactivator3(SRC-3)inhibitor

ChemicalName:1-(2-Pyridinyl)ethanone2-(1-methyl-1H-benzimidazol-2-yl)hydrazonehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentsteroidreceptorcoactivator3(SRC-3)inhibitor.ReducesSRC1,SRC2andSRC3levelsinbreastcancercelllines.Inhibitscellgrowth(IC₅₀=3.4nM),inducesapoptosisandattenuatesmigrationofMDA-MB48breastcancercellsinvitro.InhibitstumorgrowthinaMDA-MB48cellbreastcancermousemodel.Orallyavailable.

TechnicalData

M.Wt	301.78
Formula	C15H15N5.HCl
Storage	Storeat+4°C
Purity	≥98%(HPLC)
PubChemID	121513909
InChIKey	CDYJHORKRVKALB-NWBUNABESA-N
Smiles	CN1C(N/N=C(C2=CC=CC=N2)C)=NC3=CC=CC=C13.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	6.04	20
	water	15.09	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight301.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.31mL	16.57mL	33.14mL
5mM	0.66mL	3.31mL	6.63mL
10mM	0.33mL	1.66mL	3.31mL
50mM	0.07mL	0.33mL	0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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