Tocris/SKF 86002 dihydrochloride/2008/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/SKF 86002 dihydrochloride/2008/10/10 mg

Tocris/SKF 86002 dihydrochloride/2008/10/10 mg

商品编号： 2008/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:p38MAPKinhibitor;anti-inflammatoryagent

ChemicalName:6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazoledihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofp38MAPkinase(IC₅₀=0.1-1μM).PotentlyinhibitsLPS-inducedIL-1andTNF-αproductioninhumanmonocytes(IC₅₀=1μM).Alsoinhibits5-lipoxygenase-andcyclooxygenase-mediatedarachidonicacidmetabolisminRBL-1cells(IC₅₀valuesare10and100μMrespectively).Anti-inflammatoryfollowingoraladmiNISTrationinvivo.

TechnicalData

M.Wt	370.27
Formula	C₁₆H₁₂FN₃S.2HCl
Storage	Desiccateat+4°C
Purity	≥98%(HPLC)
CASNumber	116339-68-5
PubChemID	10339107
InChIKey	GQQCNUNCYVXBTF-UHFFFAOYSA-N
Smiles	Cl.Cl.FC1=CC=C(C=C1)C1=C(N2CCSC2=N1)C1=CC=NC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	18.51	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight370.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.7mL	13.5mL	27.01mL
5mM	0.54mL	2.7mL	5.4mL
10mM	0.27mL	1.35mL	2.7mL
50mM	0.05mL	0.27mL	0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

SolubilityData

PreparingStockSolutions

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