Biological Activity
A carrier of NO, relaxing smooth muscle and inhibiting platelet aggregation.
Technical Data
| M. Wt | 336.32 |
| Formula | C10H16N4O7S |
| Storage | Desiccate at -20°C |
| CAS Number | 57564-91-7 |
| PubChem ID | 104858 |
| InChI Key | HYHSBSXUHZOYLX-WDSKDSINSA-N |
| Smiles | N[C@@H](CCC(N[C@@H](CSN=O)C(NCC(O)=O)=O)=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 336.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.97 mL | 14.87 mL | 29.73 mL |
| 5 mM | 0.59 mL | 2.97 mL | 5.95 mL |
| 10 mM | 0.3 mL | 1.49 mL | 2.97 mL |
| 50 mM | 0.06 mL | 0.3 mL | 0.59 mL |
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References
References are publications that support the products' biological activity.
Bannenberg et al (1995) Characterization of the bronchodilator effects and fate of S-nitrosothiols in the isolated perfused and ventilated guinea pig lung. J.Pharmacol.Exp.Ther. 272 1238 PMID: 7891339
Gibson et al (1992) An investigation of some S-nitrosothiols, and of hydroxy-arginine, on the mouse anococcygeus. Br.J.Pharmacol. 107 715 PMID: 1472969
Radomski et al (1992) S-Nitroso-glutathione inhibits platelet activation in vitro and in vivo. Br.J.Pharmacol. 107 745 PMID: 1335336
Keywords: SNOG, supplier, NO, carrier, Breaks, down, release, ROS, Donors, Precursors, Nitric, Oxide, Signaling, Signalling, NO, Donors, /, Precursors, ROS, Donors, NO, Donors, /, Precursors, Tocris Bioscience
