Tocris/SP 141/5332/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/SP 141/5332/50/50毫克

Tocris/SP 141/5332/50/50毫克

商品编号： 5332/50

品牌： Tocris Bioscience

市场价： ¥15100.00

美元价： 9060.00

产地：美国(厂家直采)

公司：

产品分类：连接酶

公司分类： ligase

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HighaffinityMDM2inhibitor

ChemicalName:6-Methoxy-1-(1-naphthalenyl)-9H-pyrido[3,4-b]indole

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityMDM2inhibitor(K_i=28nM);directlybindsMDM2.InhibitsMDM2expressionandinducesMDM2autoubiquitinationandproteasomaldegradation.Attenuatesgrowthofbreastcancerxenografttumors.Cellpermeable.

CompoundLibraries

SP141isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	324.38
Formula	C₂₂H₁₆N₂O
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1253491-42-7
PubChemID	59620153
InChIKey	AABFWJDLCCDJJN-UHFFFAOYSA-N
Smiles	COC1=CC=C(NC2=C3C=CN=C2C4=CC=CC5=C4C=CC=C5)C3=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	32.44	100
	ethanol	32.44	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight324.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.08mL	15.41mL	30.83mL
5mM	0.62mL	3.08mL	6.17mL
10mM	0.31mL	1.54mL	3.08mL
50mM	0.06mL	0.31mL	0.62mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

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ProductDatasheets