Tocris/SPP 86/5391/50/50 mg
商品编号：
5391/50
市场价：
¥16100.00
美元价：
9660.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:PotentRETinhibitor
ChemicalName:1-(1-Methylethyl)-3-(2-phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentRETinhibitor(IC50=8nM).AlsoexhibitsinhibitoryactivityatEphA1,FGFR1,Flt4,LckandYes.InhibitsproliferationofHCT116andTPC1cellsinvitro.Cellpermeable.
CompoundLibraries
SPP86isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 277.32 |
| Formula | C16H15N5 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1357349-91-7 |
| PubChemID | 66549796 |
| InChIKey | JQOIRTDBHMDWMT-UHFFFAOYSA-N |
| Smiles | CC(C)N1N=C(C#CC3=CC=CC=C3)C2=C1N=CN=C2N |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.73 | 100 | |
| ethanol | 5.55 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight277.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.61mL | 18.03mL | 36.06mL |
| 5mM | 0.72mL | 3.61mL | 7.21mL |
| 10mM | 0.36mL | 1.8mL | 3.61mL |
| 50mM | 0.07mL | 0.36mL | 0.72mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet