Tocris/SR 7826/5626/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/SR 7826/5626/10/10 mg

Tocris/SR 7826/5626/10/10 mg

商品编号： 5626/10

品牌： Tocris Bioscience

市场价： ¥3900.00

美元价： 2340.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveLIMKinhibitor;antitumor

ChemicalName:N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveLIMKinhibitor(IC₅₀valuesare43,5536and6565nMforLIMK1,ROCKIandROCKII,respectively).InhibitscofilinphosphorylationinA7r5cellsandsuppressesmigrationandinvasionofPC-3cellsinvitro.Orallybioavailable.

TechnicalData

M.Wt	387.43
Formula	C₂₂H₂₁N₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1219728-20-7
PubChemID	45381385
InChIKey	WQAGVQVBDHOHRD-UHFFFAOYSA-N
Smiles	O=C(N(CCO)C4=CC=CC=C4)NC(C=C3)=CC=C3C1=C2C(NC=C2C)=NC=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	38.74	100
	ethanol	3.87	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight387.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.58mL	12.91mL	25.81mL
5mM	0.52mL	2.58mL	5.16mL
10mM	0.26mL	1.29mL	2.58mL
50mM	0.05mL	0.26mL	0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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